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References

For the articles below, a previous version of the program was used (make_SPM_seg_masks by Geoff Parker). The calculation using spm_segment is near identical, as illustrated in this comparison of the two methods for 17 patient datasets.

Reproducibility

The reproducibility and sensitivity of brain tissue volume measurements derived from an SPM-based segmentation methodology
Chard DT, Parker GJ, Griffin CM, Thompson AJ, Miller DH
J Magn Reson Imaging. 2002 Mar;15(3):259-67

Application

Brain atrophy in clinically early relapsing-remitting multiple sclerosis
Chard DT, Griffin CM, Parker GJ, Kapoor R, Thompson AJ, Miller DH
Brain. 2002 Feb;125(Pt 2):327-37

Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes
Dalton CM, Chard DT, Davies GR, Miszkiel KA, Altmann DR, Fernando K, Plant GT, Thompson AJ, Miller DH
Brain. 2004 May;127(Pt 5):1101-7. Epub 2004 Mar 3

Grey and white matter atrophy in early clinical stages of primary progressive multiple sclerosis
Sastre-Garriga J, Ingle GT, Chard DT, Ramio-Torrenta L, Miller DH, Thompson AJ
Neuroimage. 2004 May;22(1):353-9

Progressive grey matter atrophy in clinically early relapsing-remitting multiple sclerosis
Chard DT, Griffin CM, Rashid W, Davies GR, Altmann DR, Kapoor R, Barker GJ, Thompson AJ, Miller DH
Mult Scler. 2004 Aug;10(4):387-91

Gray and white matter volume changes in early RRMS: a 2-year longitudinal study
Tiberio M, Chard DT, Altmann DR, Davies G, Griffin CM, Rashid W, Sastre-Garriga J, Thompson AJ, Miller DH
Neurology. 2005 Mar 22;64(6):1001-7

Grey and white matter volume changes in early primary progressive multiple sclerosis: a longitudinal study
Sastre-Garriga J, Ingle GT, Chard DT, Cercignani M, Ramio-Torrenta L, Miller DH, Thompson AJ
Brain. 2005 Jun;128(Pt 6):1454-60. Epub 2005 Apr 7



Segmented Brain Image

Last modified by Jon Jackson on Wed Dec 31 11:06:47 GMT 2008


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